Article
[Investigation of the association between paraoxonase-1 gene polymorphisms and response to therapy in chronic hepatitis C patients].
Mikrobiyoloji bulteni - 1 Oct 2014
Kıratlı Kazım, Gül Hanefi Cem, Artuk Cumhur, Kozan Salih, Oztuna Ali, Tunca Yusuf, Eyigün Can Polat
Abstract excerpt
Liver-derived paraoxonase-1 (PON1) enzyme that is found in the circulation is bound to high-density lipoproteins and reduces the amount of oxidized lipids with its antioxidant effect. Humans have at least three different PON gene regions which are adjacent to the other on the 7th chromosome. It has been shown that PON1 gene and its polymorphisms are related with various diseases. It is also known that, hepatitis...
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