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Article

Rapid genotyping of paraoxonase 55 and 192 mutations by melting point analysis using real time PCR technology.

Clinica chimica acta; international journal of clinical chemistry - 1 Jun 2003

Pocsai Zsuzsa, Tóth Zsuzsa, Paragh György, Széles György, Adány Róza

Abstract excerpt

BACKGROUND: Paraoxonase (PON1) enzyme was identified as one of the components of HDL responsible for prevention of lipid peroxides accumulation in low-density lipoprotein (LDL). A triphasic phenotypic frequency distribution of PON1 activity was shown in the human population resulted by two nucleotide interchanges at residues 55 and 192. The paraoxonase isoforms have different effectiveness in hydrolysing lipid...

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Identifiers

PMID: 12763277
DOI: 10.1016/s0009-8981(03)00083-4

Genes

PON1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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