Article
Paraoxonase-1 55/192 genotypes in schizophrenic patients and their relatives in Turkish population.
Psychiatric genetics - 1 Dec 2008
Kucukali Cem Ismail, Aydin Makbule, Ozkok Elif, Orhan Nurcan, Cakir Ulku, Kilic Gamze, Ozbek Zeynep, Ince Nurhan, Kara Ihsan
Abstract excerpt
BACKGROUND: Oxidative stress and free radical-induced toxicity have been implicated in the pathophysiology of schizophrenia. In this study, we examined paraoxonase (PON1)-55/192 polymorphisms and PON1 activity in patients with schizophrenia, first-degree relatives of schizophrenic patients, and healthy controls. METHODS: This study consisted of 292 healthy participants, 267 unrelated patients with schizophrenia...
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