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Article

DNA oxidative damage in leukocytes correlates with the severity of HCV-related liver disease: validation in an open population study.

Journal of hepatology - 1 Apr 2001

Cardin R, Saccoccio G, Masutti F, Bellentani S, Farinati F, Tiribelli C

Abstract excerpt

BACKGROUND/AIMS: Oxidative DNA damage, identifiable in the formation of 8-hydroxydeoxyguanosine (8-OHdG), is relevant in the mutagenesis/carcinogenesis process. The aim of this study was to assess 8-OHdG levels in patients with hepatitis C virus (HCV) infection in relation to extent of liver damage and HCV genotype. METHODS: 8-OHdG levels were measured in DNA from circulating leukocytes of 110 anti-HCV positive...

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Identifiers

PMID: 11394660
DOI: 10.1016/s0168-8278(00)00098-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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