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Article

The influence of adenovirus fiber structure and function on vector development for gene therapy.

Molecular therapy : the journal of the American Society of Gene Therapy - 1 Sept 2005

Nicklin Stuart A, Wu Eugene, Nemerow Glen R, Baker Andrew H

Abstract excerpt

The collective attributes of adenoviruses (Ads), including ease of accomplishing replication deficiency, readily achievable high titers, encoding of large expression cassettes, efficiency of gene delivery to most cell types, and well-characterized biology, have made Ads, particularly Ad serotype 5 (Ad 5), some of the most utilized vectors for gene delivery. In recent years, however, it has become apparent that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15993650
DOI: 10.1016/j.ymthe.2005.05.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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