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Article

Mechanism of action of the oxazolidinone antibacterial agents

1 Aug 1999

Abstract excerpt

Oxazolidinones represent a new class of synthetic antibacterial agents active against multiply-resistant Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant streptococci and vancomycin-resistant enterococci. Eperezolid and linezolid are two novel analogues, which have respectively completed Phase I and Phase II clinical testing. The lack of cross-resistance...

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PMID: 15992144
DOI: 10.1517/13543784.8.8.1195

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