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Article

The site of action of oxazolidinone antibiotics in living bacteria and in human mitochondria.

Molecular cell - 11 May 2007

Leach Karen L, Swaney Steven M, Colca Jerry R, McDonald William G, Blinn James R, Thomasco Lisa M, Gadwood Robert C, Shinabarger Dean, Xiong Liqun, Mankin Alexander S

Abstract excerpt

The oxazolidinones are one of the newest classes of antibiotics. They inhibit bacterial growth by interfering with protein synthesis. The mechanism of oxazolidinone action and the precise location of the drug binding site in the ribosome are unknown. We used a panel of photoreactive derivatives t...

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Share to Acetamides
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Peptidyl Transferases

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Source

Identifiers

PMID: 17499045
DOI: 10.1016/j.molcel.2007.04.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17499045-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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