Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oxazolidinones: activity, mode of action, and mechanism of resistance.

International journal of antimicrobial agents - 1 Feb 2004

Bozdogan Bülent, Appelbaum Peter C

Abstract excerpt

Oxazolidinones are a new group of antibiotics. These synthetic drugs are active against a large spectrum of Gram-positive bacteria, including methicillin- and vancomycin-resistant staphylococci, vancomycin-resistant enterococci, penicillin-resistant pneumococci and anaerobes. Oxazolidinones inhibit protein synthesis by binding at the P site at the ribosomal 50S subunit. Resistance to other protein synthesis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetamides
Share to Anti-Infective Agents
Share to Gram-Positive Bacteria

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gram-Positive Bacterial Infections

Share to Linezolid

Share to Oxazolidinones

Share to Peptidyl Transferases

Share to RNA, Ribosomal, 23S

Source

Identifiers

PMID: 15013035
DOI: 10.1016/j.ijantimicag.2003.11.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oxazolidinones: activity, mode of action, and mechanism of resistance.PMID 15013035Read ↗

Oxazolidinones: Mechanism of action and molecular characterization of resistance mechanisms in staphylococciSemantic proximity Read ↗

Mechanism of action of the oxazolidinone antibacterial agentsSemantic proximity Read ↗

Linezolid update: stable in vitro activity following more than a decade of clinical use and summary of associated resistance mechanisms.Semantic proximity Read ↗

Linezolid: a review of its properties, function, and use in critical care.Semantic proximity Read ↗

Oxazolidinones: mechanisms of resistance and mobile genetic elements involvedSemantic proximity Read ↗

The oxazolidinones: past, present, and future.Semantic proximity Read ↗

Research progress on the oxazolidinone drug linezolid resistance.Semantic proximity Read ↗

Rχ-01, a New Family of Oxazolidinones That Overcome Ribosome-Based Linezolid ResistanceSemantic proximity Read ↗

In vitro activities of U-100592 and U-100766, novel oxazolidinone antibacterial agentsSemantic proximity Read ↗

Five-Year Summary of In Vitro Activity and Resistance Mechanisms of Linezolid against Clinically Important Gram-Positive Cocci in the United States from the LEADER Surveillance Program (2011 to 2015)Semantic proximity Read ↗

Linezolid Resistance in StaphylococciSemantic proximity Read ↗

Biological Effects of Quinolones: A Family of Broad-Spectrum Antimicrobial AgentsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.