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Article

Linezolid: a review of its properties, function, and use in critical care.

Drug design, development and therapy - 1 Jan 2018

Hashemian Seyed Mohammad Reza, Farhadi Tayebeh, Ganjparvar Mojdeh

Abstract excerpt

Linezolid can be considered as the first member of the class of oxazolidinone antibiotics. The compound is a synthetic antibiotic that inhibits bacterial protein synthesis through binding to rRNA. It also inhibits the creation of the initiation complex during protein synthesis which can reduce the length of the developed peptide chains, and decrease the rate of reaction of translation elongation. Linezolid has...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29950810
DOI: 10.2147/DDDT.S164515
PMCID: PMC6014438

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