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Article

Somatic mutations in the mitochondria of rheumatoid arthritis synoviocytes.

Arthritis research & therapy - 1 Jan 2005

Da Sylva Tanya R, Connor Alison, Mburu Yvonne, Keystone Edward, Wu Gillian E

Abstract excerpt

Somatic mutations have a role in the pathogenesis of a number of diseases, particularly cancers. Here we present data supporting a role of mitochondrial somatic mutations in an autoimmune disease, rheumatoid arthritis (RA). RA is a complex, multifactorial disease with a number of predisposition traits, including major histocompatibility complex (MHC) type and early bacterial infection in the joint. Somatic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15987486
DOI: 10.1186/ar1752
PMCID: PMC1175034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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