HPRT- mutant T cells in the peripheral blood and synovial tissue of patients with rheumatoid arthritis.

doi:10.1002/1529-0131(199810)41:10<1772::AID-ART9>3.0.CO;2-C

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Article

HPRT- mutant T cells in the peripheral blood and synovial tissue of patients with rheumatoid arthritis.

Arthritis and rheumatism - 1 Oct 1998

Cannons J L, Karsh J, Birnboim H C, Goldstein R

Abstract excerpt

OBJECTIVE: To investigate the frequency and characteristics of hprt- mutant T lymphocytes in the peripheral blood and synovium of rheumatoid arthritis (RA) patients compared with controls, and to correlate these findings with disease parameters. METHODS: An hprt- T cell assay was performed on blo...

Topics

Adult
Aged
Arthritis, Rheumatoid
Cell Adhesion
Cell Line
Cloning, Molecular
Female
Humans
Hypoxanthine Phosphoribosyltransferase
Male
Middle Aged
Mutation
Osteoarthritis
Synovial Membrane
T-Lymphocytes

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