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Article

Mitochondrial mutagenesis correlates with the local inflammatory environment in arthritis.

Annals of the rheumatic diseases - 1 Apr 2012

Harty Leonard C, Biniecka Monika, O'Sullivan Jacintha, Fox Edward, Mulhall Kevin, Veale Douglas J, Fearon Ursula

Abstract excerpt

BACKGROUND: To examine the association between mitochondrial mutagenesis and the proinflammatory microenvironment in patients with inflammatory arthritis. METHODS: Fifty patients with inflammatory arthritis underwent arthroscopy and synovial tissue biopsies, synovial fluid and clinical assessment were obtained. Fifteen patients pre/post-TNFi therapy were also recruited. Normal synovial biopsies were obtained from...

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Identifiers

PMID: 22121133
DOI: 10.1136/annrheumdis-2011-200245

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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