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Article

Roles of steroid receptor coactivator (SRC)-1 and transcriptional intermediary factor (TIF) 2 in androgen receptor activity in mice.

Proceedings of the National Academy of Sciences of the United States of America - 5 Jul 2005

Ye Xiangcang, Han Sang Jun, Tsai Sophia Y, DeMayo Francesco J, Xu Jianming, Tsai Ming-Jer, O'Malley Bert W

Abstract excerpt

Genetic disruption of the steroid receptor coactivator (SRC)-1 and transcriptional intermediary factor (TIF)2/SRC-2 in mouse resulted in distinctive mutant phenotypes. To quantify their roles in the function of androgen receptor (AR) transcriptional activity in vivo, we generated a unique transgenic AR-reporter mouse and analyzed the cell-specific contributions of SRC-1 and TIF2 to the activity of AR in mouse...

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Identifiers

PMID: 15983373
DOI: 10.1073/pnas.0503577102
PMCID: PMC1172261

Genes

SRC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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