Article
Differential gene regulation by the SRC family of coactivators.
Genes & development - 15 Jul 2004
Zhang Hua, Yi Xia, Sun Xiaojing, Yin Na, Shi Bin, Wu Huijian, Wang Dan, Wu Ge, Shang Yongfeng
Abstract excerpt
SRCs (steroid receptor coactivators) are required for nuclear receptor-mediated transcription and are also implicated in the transcription initiation by other transcription factors, such as STATs and NFkappaB. Despite phenotypic manifestations in gene knockout mice for SRC-1, GRIP1, and AIB1 of the SRC (Steroid Receptor Coactivator) family indicating their differential roles in animal physiology, there is no...
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