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Article

Maternal factors in a model of type 1 diabetes differentially affect the development of insulitis and overt diabetes in offspring.

Diabetes - 1 Jul 2005

Kagohashi Yukiko, Udagawa Jun, Abiru Norio, Kobayashi Masakazu, Moriyama Kenji, Otani Hiroki

Abstract excerpt

Type 1 diabetes, a multifactorial disease involving genetic and environmental factors, results from the destruction of pancreatic beta-cells. The maternal environment has been suggested to be important in the development of diabetes. To assess the role of maternal factors in the development of insulitis and overt diabetes, we transplanted pre-implantation stage embryos of nonobese diabetic (NOD) mice, a model of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15983203
DOI: 10.2337/diabetes.54.7.2026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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