Article
Maternal environment affects endogenous virus induction in the offspring of type 1 diabetes model non-obese diabetic mice.
Congenital anomalies - 1 Sept 2005
Kagohashi Yukiko, Udagawa Jun, Moriyama Kenji, Otani Hiroki
Abstract excerpt
Type 1 diabetes results from the destruction of pancreatic b-cells (insulitis). It is a multifactorial disease involving genetic and environmental factors, including the maternal environment. Viruses have also been implicated in the pathogenesis of human type 1 diabetes as well as in its model non-obese diabetic (NOD) mice during the perinatal period, as endogenous viruses and/or as infectious agents vertically...
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