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Article

<i>Foxl2</i> gene and the development of the ovary: a story about goat, mouse, fish and woman

1 May 2005

Abstract excerpt

In this review, we describe recent results concerning the genetics of sex determination in mammals. Particularly, we developed the study of the FOXL2 gene and its implication in genetic anomalies in goats (PIS mutation) and humans (BPES). We present the expression of FOXL2 in the ovaries of different species.

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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Identifiers

PMID: 15982462
DOI: 10.1051/rnd:2005028

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

<i>Foxl2</i> gene and the development of the ovary: a story about goat, mouse, fish and womanPMID 15982462Read ↗

Telling the story of XX sex reversal in the goat: highlighting the sex-crossroad in domestic mammals.Semantic proximity Read ↗

FOXL2 activates <i>P450 aromatase</i> gene transcription: towards a better characterization of the early steps of mammalian ovarian developmentSemantic proximity Read ↗

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Positional cloning of the PIS mutation in goats and its impact on understanding mammalian sex-differentiation.Semantic proximity Read ↗

Attempt to rescue sex-reversal by transgenic expression of the PISRT1 gene in XX PIS-/- goats.Semantic proximity Read ↗

The Genetics and Biology of FOXL2.Semantic proximity Read ↗

Ovarian-specific expression of a new gene regulated by the goat PIS region and transcribed by a FOXL2 bidirectional promoter.Semantic proximity Read ↗

<i>FOXL2 </i>Impairment in Human DiseaseSemantic proximity Read ↗

Involvement of FOXL2 and RSPO1 in Ovarian Determination, Development, and Maintenance in MammalsSemantic proximity Read ↗

R-spondin1 and FOXL2act into two distinct cellular types during goat ovarian differentiationSemantic proximity Read ↗

High-Throughput Sequencing Analyses of XX Genital Ridges Lacking FOXL2 Reveal DMRT1 Up-Regulation Before SOX9 Expression During the Sex-Reversal Process in Goats1Semantic proximity Read ↗

Genetics of Ovarian Differentiation: <i>Rspo1</i>, a Major PlayerSemantic proximity Read ↗

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