Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Telling the story of XX sex reversal in the goat: highlighting the sex-crossroad in domestic mammals.

Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation - 1 Jan 2012

Pannetier M, Elzaiat M, Thépot D, Pailhoux E

Abstract excerpt

The conditions for sex reversal in vertebrate species have been studied extensively and have highlighted numerous key factors involved in sex differentiation. We review here the history of the development of knowledge, referring to one example of complete female-to-male XX sex reversal associated with a polled phenotype in the goat. The results and hypotheses concerning this polled intersex syndrome (PIS) are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disorders of Sex Development
Share to Estrogens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Forkhead Transcription Factors

Share to Goat Diseases

Share to Sex Differentiation

Share to Steroids

Source

Identifiers

PMID: 22094227
DOI: 10.1159/000334056

Genes

FOXL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Telling the story of XX sex reversal in the goat: highlighting the sex-crossroad in domestic mammals.PMID 22094227Read ↗

Positional cloning of the PIS mutation in goats and its impact on understanding mammalian sex-differentiation.Semantic proximity Read ↗

Ontogenesis of female-to-male sex-reversal in XX polled goats.Semantic proximity Read ↗

Expression studies of the PIS-regulated genes suggest different mechanisms of sex determination within mammals.Semantic proximity Read ↗

<i>Foxl2</i> gene and the development of the ovary: a story about goat, mouse, fish and womanSemantic proximity Read ↗

Sex Reversal in Non-Human Placental MammalsSemantic proximity Read ↗

Attempt to rescue sex-reversal by transgenic expression of the PISRT1 gene in XX PIS-/- goats.Semantic proximity Read ↗

High-Throughput Sequencing Analyses of XX Genital Ridges Lacking FOXL2 Reveal DMRT1 Up-Regulation Before SOX9 Expression During the Sex-Reversal Process in Goats1Semantic proximity Read ↗

Molecular analysis of 60,XX pseudohermaphrodite polled goats for the presence of SRY and ZFY genes.Semantic proximity Read ↗

Single-cell RNA sequencing analysis reveals new insights for intersex gonad initiation and early sex differentiation of goatsSemantic proximity Read ↗

FOXL2 activates <i>P450 aromatase</i> gene transcription: towards a better characterization of the early steps of mammalian ovarian developmentSemantic proximity Read ↗

Ovarian-specific expression of a new gene regulated by the goat PIS region and transcribed by a FOXL2 bidirectional promoter.Semantic proximity Read ↗

R-spondin1 and FOXL2act into two distinct cellular types during goat ovarian differentiationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.