Article
Genetics of Ovarian Differentiation: <i>Rspo1</i>, a Major Player
1 Jan 2008
Abstract excerpt
In mammals, the sex of the embryo is determined during development by its commitment either to the male or female genetic program regulating testicular or ovarian organogenesis. Major steps towards unraveling sex determination in mammals are achieved by the identification of key genes involved in human pathologies and the application of mouse genetics to analyze their function. While the expression of Sry and...
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