Article
FOXL2 activates <i>P450 aromatase</i> gene transcription: towards a better characterization of the early steps of mammalian ovarian development
21 Feb 2006
Abstract excerpt
Previous studies have equated FOXL2 as a crucial actor in the ovarian differentiation process in different vertebrate species. Its transcriptional extinction in the polled intersex syndrome (PIS) leads primarily to a drastic decrease of aromatase (CYP19) expression in the first steps of goat ovarian development. In this study, we provide a better characterization of early ovarian development in goat, and we...
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