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Article

Positional cloning of the PIS mutation in goats and its impact on understanding mammalian sex-differentiation.

Genetics, selection, evolution : GSE - 1 Jan 2005

Pailhoux Eric, Vigier Bernard, Schibler Laurent, Cribiu Edmond P, Cotinot Corinne, Vaiman Daniel

Abstract excerpt

In goats, the PIS (polled intersex syndrome) mutation is responsible for both the absence of horns in males and females and sex-reversal affecting exclusively XX individuals. The mode of inheritance is dominant for the polled trait and recessive for sex-reversal. In XX PIS-/- mutants, the express...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15601595
DOI: 10.1186/1297-9686-37-S1-S55
PMCID: PMC3226265

Genes

FOXL2
SOX9
SRY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15601595-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Positional cloning of the PIS mutation in goats and its impact on understanding mammalian sex-differentiation.PMID 15601595Read ↗

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