Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Constitutive soxR mutations contribute to multiple-antibiotic resistance in clinical Escherichia coli isolates.

Antimicrobial agents and chemotherapy - 1 Jul 2005

Koutsolioutsou Anastasia, Peña-Llopis Samuel, Demple Bruce

Abstract excerpt

The soxRS regulon of Escherichia coli and Salmonella enterica is induced by redox-cycling compounds or nitric oxide and provides resistance to superoxide-generating agents, macrophage-generated nitric oxide, antibiotics, and organic solvents. We have previously shown that constitutive expression of soxRS can contribute to quinolone resistance in clinically relevant S. enterica. In this work, we have carried out...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance, Multiple, Bacterial

Share to Escherichia coli

Share to Escherichia coli Proteins

Share to Gene Expression Regulation, Bacterial

Share to Microbial Sensitivity Tests

Share to Trans-Activators

Source

Open in PubMed Open full text

Identifiers

PMID: 15980345
DOI: 10.1128/AAC.49.7.2746-2752.2005
PMCID: PMC1168631

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Constitutive soxR mutations contribute to multiple-antibiotic resistance in clinical Escherichia coli isolates.PMID 15980345Read ↗

A soxRS-constitutive mutation contributing to antibiotic resistance in a clinical isolate of Salmonella enterica (Serovar typhimurium).Semantic proximity Read ↗

A novel alanine to serine substitution mutation in SoxS induces overexpression of efflux pumps and contributes to multidrug resistance in clinical <i>Escherichia coli</i> isolatesSemantic proximity Read ↗

Characterization of spontaneous mutation in the delta soxR and SoxS overproducing strains of Escherichia coli.Semantic proximity Read ↗

Constitutive SoxS Expression in a Fluoroquinolone-Resistant Strain with a Truncated SoxR Protein and Identification of a New Member of themarA-soxS-robRegulon,mdtGSemantic proximity Read ↗

Global regulator SoxR is a negative regulator of efflux pump gene expression and affects antibiotic resistance and fitness in Acinetobacter baumannii.Semantic proximity Read ↗

Nitrofurantoin, phenazopyridine, and the superoxide-response regulon soxRS of Escherichia coli.Semantic proximity Read ↗

Transcription-defective soxR mutants of Escherichia coli: isolation and in vivo characterization.Semantic proximity Read ↗

Activation of the SoxR regulon in Streptomyces coelicolor by the extracellular form of the pigmented antibiotic actinorhodin.Semantic proximity Read ↗

Activation of oxidative stress genes by mutations at the soxQ/cfxB/marA locus of Escherichia coli.Semantic proximity Read ↗

Genetic relationship between soxRS and mar loci in promoting multiple antibiotic resistance in Escherichia coli.Semantic proximity Read ↗

A reducing system of the superoxide sensor SoxR in Escherichia coli.Semantic proximity Read ↗

Two-stage induction of the soxRS (superoxide response) regulon of Escherichia coli.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.