Article
Genetic relationship between soxRS and mar loci in promoting multiple antibiotic resistance in Escherichia coli.
Antimicrobial agents and chemotherapy - 1 Aug 1994
Miller P F, Gambino L F, Sulavik M C, Gracheck S J
Abstract excerpt
Multiple antibiotic resistance in Escherichia coli has typically been associated with mutations at the mar locus, located at 34 min on the E. coli chromosome. A new mutant, marC, isolated on the basis of a Mar phenotype but which maps to the soxRS (encoding the regulators of the superoxide stress response) locus located at 92 min, is described here. This mutant shares several features with a known constitutive...
Topics
- Alleles
- Bacterial Outer Membrane Proteins
- Bacterial Proteins
- Chromosome Mapping
- DNA-Binding Proteins
- Drug Resistance, Microbial
- Escherichia coli
- Escherichia coli Proteins
- Genes, Bacterial
- Superoxides