Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic relationship between soxRS and mar loci in promoting multiple antibiotic resistance in Escherichia coli.

Antimicrobial agents and chemotherapy - 1 Aug 1994

Miller P F, Gambino L F, Sulavik M C, Gracheck S J

Abstract excerpt

Multiple antibiotic resistance in Escherichia coli has typically been associated with mutations at the mar locus, located at 34 min on the E. coli chromosome. A new mutant, marC, isolated on the basis of a Mar phenotype but which maps to the soxRS (encoding the regulators of the superoxide stress response) locus located at 92 min, is described here. This mutant shares several features with a known constitutive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Bacterial Proteins
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Drug Resistance, Microbial

Share to Escherichia coli

Share to Genes, Bacterial

Share to Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 7986007
DOI: 10.1128/AAC.38.8.1773
PMCID: PMC284635

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic relationship between soxRS and mar loci in promoting multiple antibiotic resistance in Escherichia coli.PMID 7986007Read ↗

Repressor mutations in the marRAB operon that activate oxidative stress genes and multiple antibiotic resistance in Escherichia coli.Semantic proximity Read ↗

Activation of oxidative stress genes by mutations at the soxQ/cfxB/marA locus of Escherichia coli.Semantic proximity Read ↗

marA, a regulated locus which controls expression of chromosomal multiple antibiotic resistance in Escherichia coli.Semantic proximity Read ↗

Proteolytic degradation of Escherichia coli transcription activators SoxS and MarA as the mechanism for reversing the induction of the superoxide (SoxRS) and multiple antibiotic resistance (Mar) regulons.Semantic proximity Read ↗

Constitutive soxR mutations contribute to multiple-antibiotic resistance in clinical Escherichia coli isolates.Semantic proximity Read ↗

A soxRS-constitutive mutation contributing to antibiotic resistance in a clinical isolate of Salmonella enterica (Serovar typhimurium).Semantic proximity Read ↗

Transcription-defective soxR mutants of Escherichia coli: isolation and in vivo characterization.Semantic proximity Read ↗

The multiple antibiotic resistance (mar) locus and its significance.Semantic proximity Read ↗

Nitrofurantoin, phenazopyridine, and the superoxide-response regulon soxRS of Escherichia coli.Semantic proximity Read ↗

Two-stage induction of the soxRS (superoxide response) regulon of Escherichia coli.Semantic proximity Read ↗

soxR, a locus governing a superoxide response regulon in Escherichia coli K-12.Semantic proximity Read ↗

Fis, an accessorial factor for transcriptional activation of the mar (multiple antibiotic resistance) promoter of Escherichia coli in the presence of the activator MarA, SoxS, or Rob.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.