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Article

A soxRS-constitutive mutation contributing to antibiotic resistance in a clinical isolate of Salmonella enterica (Serovar typhimurium).

Antimicrobial agents and chemotherapy - 1 Jan 2001

Koutsolioutsou A, Martins E A, White D G, Levy S B, Demple B

Abstract excerpt

The soxRS regulon is activated by redox-cycling drugs such as paraquat and by nitric oxide. The >15 genes of this system provide resistance to both oxidants and multiple antibiotics. An association between clinical quinolone resistance and elevated expression of the soxRS regulon has been observed in Escherichia coli, but this association has not been explored for other enteropathogenic bacteria. Here we describe...

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Identifiers

PMID: 11120941
DOI: 10.1128/AAC.45.1.38-43.2001
PMCID: PMC90236

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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