Article
Characterization of spontaneous mutation in the delta soxR and SoxS overproducing strains of Escherichia coli.
Journal of radiation research - 1 Jun 2002
Yamamura Eiji, Lee Eun Hye, Kuzumaki Akihiro, Uematsu Norio, Nunoshiba Tatsuo, Kawata Masakado, Yamamoto Kazuo
Abstract excerpt
To examine the role of the soxRS regulon in mutagenesis, we characterized the spontaneous mutations occurring in the endogenous tonB gene in the delta soxR strain and the SoxS overproducing strain of Escherichia coli. Neither the delta soxR strain nor the SoxS overproducing strain led to an enhancement or diminishment of the spontaneous mutation frequency. By DNA sequencing, we determined 50 spontaneous mutants...
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