Article
pain1: a neuropathic pain QTL on mouse chromosome 15 in a C3HxC58 backcross.
Pain - 1 Aug 2005
Devor Marshall, Gilad Amit, Arbilly Michal, Yakir Benjamin, Raber Pnina, Pisanté Anne, Darvasi Ariel
Abstract excerpt
We have produced a backcross (BC) population of 267 mice from the parental strains C3H/HeN and C58/J. The mice were phenotyped for neuropathic pain using the neuroma model. Subsequently all BC mice were genotyped in a region of chromosome 15 that has been previously suggested to contain a quantitative trait locus (QTL) for this trait. We have confirmed the linkage of the QTL, named pain1, to the central region of...
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