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Article

Sex-specific variability and a 'cage effect' independently mask a neuropathic pain quantitative trait locus detected in a whole genome scan.

The European journal of neuroscience - 1 Aug 2007

Devor Marshall, Gilad Amit, Arbilly Michal, Nissenbaum Jonathan, Yakir Benjamin, Raber Pnina, Minert Anne, Pisanté Anne, Darvasi Ariel

Abstract excerpt

Sex and environment may dramatically affect genetic studies, and thus should be carefully considered. Beginning with two inbred mouse strains with contrasting phenotype in the neuroma model of neuropathic pain (autotomy), we established a backcross population on which we conducted a genome-wide scan. The backcross population was partially maintained in small social groups and partially in isolation. The genome...

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Source

Identifiers

PMID: 17686043
DOI: 10.1111/j.1460-9568.2007.05704.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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