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Genetic mapping in Diversity Outbred mice identifies a <i>Trpa1</i> variant influencing late phase formalin response

2018-07-05

Abstract excerpt

<h4>ABSTRACT</h4> Identification of genetic variants that influence susceptibility to chronic pain is key to identifying molecular mechanisms and targets for effective and safe therapeutic alternatives to opioids. To identify genes and variants associated with chronic pain, we measured late phase response to formalin injection in 275 male and female Diversity Outbred (DO) mice genotyped for over 70 thousand SNPs....

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Literature Corpus work
6ccd2bfc-b06d-599b-aabd-7e3bde50afdc
DOI
10.1101/362855
Open publication

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Genetic mapping in Diversity Outbred mice identifies a <i>Trpa1</i> variant influencing late phase formalin responseDOI 10.1101/362855
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