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Article

ENU induced single mutation locus on chr 16 leads to high-frequency hearing loss in mice.

Genes & genetic systems - 1 Jun 2009

Jiao Yan, Cai Chun, Kermany Mohammad Habiby, Yan Jian, Cai Qing, Miller Darla, Goldowitz Daniel, Li Xinmin, Yoo Tai-June, Gu Weikuan

Abstract excerpt

The hallmark of age-related (presbycusis) and noise-induced hearing loss is high-frequency (> 20 kHz) hearing loss. Through a collaborative study with TMGC (Tennessee Mouse Genome Consortium), seventeen ENU-induced mouse mutation strains with high-frequency hearing loss have been identified, but affected genes are yet identified. As a first step in identifying the gene/s underlying the ENU mutations, we created a...

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Identifiers

PMID: 19745570
DOI: 10.1266/ggs.84.219
PMCID: PMC3155952

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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