Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oxidative Stress Decreases Klotho Expression in a Mouse Kidney Cell Line

22 Jun 2005

Abstract excerpt

BACKGROUND/AIMS: Defects in klotho gene expression in the mouse result in a syndrome that resembles human aging. We recently identified expression of klotho in a mouse inner medullary collecting duct (mIMCD3) cell line for the first time, and in the present study we explored the physiological relevance of the regulation of klotho expression in the presence of oxidant stress injury. METHODS: Klotho expression was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Kidney Cyst Diseases
Share to Heterotopic Ossification and Related Conditions
Share to Parathyroid Disorders and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15976510
DOI: 10.1159/000086500

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oxidative Stress Decreases Klotho Expression in a Mouse Kidney Cell LinePMID 15976510Read ↗

Klotho attenuates renal hypertrophy and glomerular injury in Ins2Akita diabetic mice.Semantic proximity Read ↗

Improvement of multiple pathophysiological phenotypes of klotho (kl/kl) mice by adenovirus-mediated expression of the klotho gene.Semantic proximity Read ↗

Amelioration of progressive renal injury by genetic manipulation of <i>Klotho</i> geneSemantic proximity Read ↗

Suppression of Aging in Mice by the Hormone KlothoSemantic proximity Read ↗

The Antisenescence Protein Klotho Is Necessary for FGF23-Induced PhosphaturiaSemantic proximity Read ↗

Mutation of the mouse klotho gene leads to a syndrome resembling ageing.Semantic proximity Read ↗

Klotho-derived peptide 1 inhibits cellular senescence in the fibrotic kidney by restoring Klotho expression via posttranscriptional regulationSemantic proximity Read ↗

Epigenetic modifications of Klotho expression in kidney diseasesSemantic proximity Read ↗

Molecular Basis of Klotho: From Gene to Function in AgingSemantic proximity Read ↗

Klotho: a fundamental regulator of aging.Semantic proximity Read ↗

Upstream and downstream regulators of Klotho expression in chronic kidney diseaseSemantic proximity Read ↗

Epigenetic Regulation of KL (Klotho) via H3K27me3 (Histone 3 Lysine [K] 27 Trimethylation) in Renal Tubule CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.