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Article

Bronchodilator response in relation to beta2-adrenoceptor haplotype in patients with asthma.

American journal of respiratory and critical care medicine - 15 Sept 2005

Taylor D Robin, Epton Michael J, Kennedy Martin A, Smith Andrew D, Iles Steven, Miller Allison L, Littlejohn Matthew D, Cowan Jan O, Hewitt Tracey, Swanney Maureen P, Brassett Karen P, Herbison G Peter

Abstract excerpt

RATIONALE: Genetic variation of the beta2-adrenoceptor (ADRB2) influences receptor function in vitro. There are reports that, in vivo, bronchodilator response is related to ADRB2 genotype, and that clinical outcomes during chronic therapy with beta2-agonist drugs are also influenced by genotype. Whether these features are related to single nucleotide polymorphisms or to combinations (haplotypes) is unclear....

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Share to Adrenergic beta-Agonists
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Receptors, Adrenergic, beta-2

Source

Identifiers

PMID: 15976384
DOI: 10.1164/rccm.200501-092OC

Genes

ADRB2
FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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