Article
Limited beta2-adrenoceptor haplotypes display different agonist mediated airway responses in asthmatics.
Respiratory research - 31 Jan 2006
van Veen Anneke, Wierenga Eddy A, Westland Robert, Weller Frank R, Hart Guus A M, Jansen Henk M, Jonkers René E
Abstract excerpt
BACKGROUND: In vitro and some in vivo studies suggested that genetic haplotypes may have an impact on beta2-agonist mediated airway responses in asthmatics. Due to strong linkage disequilibrium the single nucleotide polymorphisms (SNPs) in the beta2-adrenoceptor gene result in only a limited numb...
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