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Article

Determination of beta2-adrenergic receptor (ADRB2) haplotypes by a multiplexed polymerase chain reaction assay.

Human mutation - 1 Dec 2002

Littlejohn Mathew D, Taylor D Robin, Miller Allison L, Kennedy Martin A

Abstract excerpt

The beta2-adrenergic receptor (B2AR or ADRB2) is the target of beta2-agonist drugs used for bronchodilation in asthma and other respiratory diseases. The gene for this receptor (ADRB2) contains numerous single nucleotide polymorphisms (SNPs) some of which may be of pharmacogenetic relevance, although a consistent picture of genotype-phenotype relationships has yet to emerge. Recently, 12 distinct haplotypes of...

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Share to Asthma
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymerase Chain Reaction

Share to Polymorphism, Single Nucleotide

Share to Receptors, Adrenergic, beta

Share to Sensitivity and Specificity

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 12442282
DOI: 10.1002/humu.9091

Genes

ADRB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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