Article
Beta(2)-adrenergic receptor polymorphisms and response to salbutamol among Indian asthmatics*.
Pharmacogenomics - 1 Jun 2005
Kukreti Ritushree, Bhatnagar Pallav, B-Rao Chandrika, Gupta Simone, Madan Babita, Das Chinmoyee, Guleria Randeep, Athavale Amita Umesh, Brahmachari Samir Kumar, Ghosh Balaram
Abstract excerpt
INTRODUCTION: The beta(2)-adrenergic receptor (beta(2)AR or ADRbeta(2)) is the target for beta(2)-agonist drugs used for bronchodilation in asthma and other respiratory diseases. The aim of this study was to identify common single nucleotide polymorphisms (SNPs) and haplotypes in asthmatics and healthy individuals from an Indian population, and determine the influence of beta(2)AR SNPs in responsiveness to...
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