Article
C-C chemokine receptor 5 gene variants in relation to lung disease in sarcoidosis.
American journal of respiratory and critical care medicine - 15 Sept 2005
Spagnolo Paolo, Renzoni Elisabetta A, Wells Athol U, Copley Susan J, Desai Sujal R, Sato Hiroe, Grutters Jan C, Abdallah Atiyeh, Taegtmeyer Anne, du Bois Roland M, Welsh Kenneth I
Abstract excerpt
RATIONALE: Genetic factors are likely to influence the clinical course and pattern of sarcoidosis, a granulomatous disease of unknown origin. OBJECTIVES: We tested this hypothesis for C-C chemokine receptor 5 (CCR5), a molecule involved in recruitment and activation of mononuclear cells. METHODS:...
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