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Article

CARD15/NOD2 polymorphisms are associated with severe pulmonary sarcoidosis.

The European respiratory journal - 1 Feb 2010

Sato H, Williams H R T, Spagnolo P, Abdallah A, Ahmad T, Orchard T R, Copley S J, Desai S R, Wells A U, du Bois R M, Welsh K I

Abstract excerpt

Sarcoidosis and Crohn's disease are heterogeneous systemic diseases characterised by granulomatous inflammation. Caspase recruitment domain (CARD)15 is a major susceptibility gene for Crohn's disease, and specifically for ileal and fibrostenotic subtypes. The C-C chemokine receptor (CCR)5 gene has been associated with both parenchymal pulmonary sarcoidosis and perianal Crohn's disease. This study explored...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19679608
DOI: 10.1183/09031936.00010209

Genes

CCR5
NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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