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Article

Interferon regulatory factor 5 polymorphisms in sarcoidosis.

Modern rheumatology - 1 Nov 2013

Tanizawa Kiminobu, Handa Tomohiro, Nagai Sonoko, Sato Hiroe, Yamada Ryo, Ito Isao, Kubo Takeshi, Ito Yutaka, Watanabe Kizuku, Aihara Kensaku, Ikezoe Kohei, Mishima Michiaki, Izumi Takateru

Abstract excerpt

OBJECTIVE: Interferon regulatory factor 5 (IRF5) gene polymorphisms are associated with susceptibility to autoimmune diseases. The aim of this study is to determine the roles of IRF5 single-nucleotide polymorphisms (SNPs) in sarcoidosis. METHODS: A total of 175 Japanese patients with biopsy-proven sarcoidosis and 150 sex-matched controls were genotyped for four IRF5 SNPs: rs729302A/C, rs2004640G/T, rs10954213A/G,...

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PMID: 23288367
DOI: 10.1007/s10165-012-0814-7

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