Article
A novel role for integrin-linked kinase in epithelial sheet morphogenesis.
Molecular biology of the cell - 1 Sept 2005
Vespa Alisa, D'Souza Sudhir J A, Dagnino Lina
Abstract excerpt
Integrin-linked kinase (ILK) is a multidomain protein involved in cell motility and cell-extracellular matrix interactions. ILK is found in integrin-containing focal adhesions in undifferentiated primary epidermal keratinocytes. Induction of keratinocyte differentiation by treatment with Ca(2+) triggers formation of cell-cell junctions, loss of focal adhesions, and ILK distribution to cell borders. We now show...
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