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Article

Analysis of genetic polymorphisms in acetylcholinesterase as reflected in different populations.

Current Alzheimer research - 1 Apr 2005

Hasin Yehudit, Avidan Nili, Bercovich Dani, Korczyn Amos D, Silman Israel, Beckmann Jacques S, Sussman Joel L

Abstract excerpt

Acetylcholinesterase (AChE) plays a crucial physiological role in termination of impulse transmission at cholinergic synapses through rapid hydrolysis of acetylcholine. In addition, it was implicated in amyloid plaque formation, a hallmark of Alzheimer's disease (AD), and most of the drugs used in AD treatment are AChE inhibitors. Thus ACHE is an obvious candidate gene for pharmacogenetic study of AD treatment....

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Identifiers

PMID: 15974920
DOI: 10.2174/1567205053585909

Genes

ACHE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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