Article
Genetic and environmental epidemiology of Alzheimer's disease in arabs residing in Israel.
Journal of molecular neuroscience : MN - 1 Jan 2003
Farrer Lindsay A, Friedland Robert P, Bowirrat Abdalla, Waraska Kristin, Korczyn Amos, Baldwin Clinton T
Abstract excerpt
We have found an unusually high prevalence of Alzheimer's disease (AD) in Wadi Ara, an inbred Arab community in northern Israel. Allele frequencies of 4.5% and 3.5% were found for the apolipoprotein E e4 allele among AD cases and nondemented controls, respectively, showing that other genetic or environmental influences must be responsible. Family studies revealed that more than one-third of the AD cases are...
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