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Article

A paradigm for single nucleotide polymorphism analysis: the case of the acetylcholinesterase gene.

Human mutation - 1 Nov 2004

Hasin Yehudit, Avidan Nili, Bercovich Dani, Korczyn Amos, Silman Israel, Beckmann Jacques S, Sussman Joel L

Abstract excerpt

Acetylcholinesterase (AChE) plays a crucial physiological role in termination of impulse transmission at cholinergic synapses through rapid hydrolysis of acetylcholine. It is a highly conserved molecule, and only a few naturally occurring genetic polymorphisms have been reported in the human gene. The goal of the present study was to make a systematic effort to identify natural single nucleotide polymorphisms...

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PMID: 15459952
DOI: 10.1002/humu.20106

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ACHE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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