Article
Identification of multiple loci for Alzheimer disease in a consanguineous Israeli-Arab community.
Human molecular genetics - 15 Feb 2003
Farrer Lindsay A, Bowirrat Abdalla, Friedland Robert P, Waraska Kristin, Korczyn Amos D, Baldwin Clinton T
Abstract excerpt
We have observed an unusually high prevalence of dementia of the Alzheimer type (DAT) in Wadi Ara, an inbred Arab community in northern Israel comprising approximately 850 persons over the age of 60 years. Family studies revealed that more than one-third of the DAT cases are members of one hamula (tribal group) within Wadi Ara. To map chromosomal loci contributing to DAT susceptibility, we conducted a 10 cM scan...
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