Article
High resolution studies of the Xenopus laevis ribosomal gene promoter in vivo and in vitro.
The Journal of biological chemistry - 5 Jun 1992
Read C, Larose A M, Leblanc B, Bannister A J, Firek S, Smith D R, Moss T
Abstract excerpt
The first high resolution maps of the Xenopus laevis ribosomal promoter and its flanking regions (-179 to +14) have been created by assaying point mutants both in oocyte and in vitro. Within the promoter boundaries (-141(-145) to +3(+4)), domains analogous to the Core Promoter and "Upstream Control Element" (UCE) were clearly detected. The base pairs at -133, within the UCE, and -20, -10, -7, and +3, within the...
Topics
- Animals
- Base Sequence
- DNA Fingerprinting
- DNA, Ribosomal
- DNA-Binding Proteins
- Molecular Sequence Data
- Mutation
- Plasmids
- Pol1 Transcription Initiation Complex Proteins
- Promoter Regions, Genetic
