A system to study transcription by yeast RNA polymerase I within the chromosomal context: functional analysis of the ribosomal DNA enhancer and the RBP1/REB1 binding sites.

doi:10.1002/j.1460-2075.1992.tb05568.x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

A system to study transcription by yeast RNA polymerase I within the chromosomal context: functional analysis of the ribosomal DNA enhancer and the RBP1/REB1 binding sites.

The EMBO journal - 1 Dec 1992

Kulkens T, van der Sande C A, Dekker A F, van Heerikhuizen H, Planta R J

Abstract excerpt

We have developed a novel system to study transcription by yeast RNA polymerase I (Pol I) of mutated rDNA units within the chromosomal context. For this, complete rDNA units carrying specific oligonucleotide tags in both the 17S and 26S rRNA genes were integrated into the chromosomal rDNA locus. Using this novel system, we analysed the action of the rDNA enhancer in stimulating transcription within the...

Topics

Base Sequence
Binding Sites
Blotting, Northern
Chromosomes, Fungal
DNA, Fungal
DNA, Ribosomal
DNA-Binding Proteins
Enhancer Elements, Genetic
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

RNA Polymerase I

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Sequence Deletion

Transcription Factors

Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 1425596
DOI: 10.1002/j.1460-2075.1992.tb05568.x
PMCID: PMC557042

Genes

RBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1425596-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A system to study transcription by yeast RNA polymerase I within the chromosomal context: functional analysis of the ribosomal DNA enhancer and the RBP1/REB1 binding sites.PMID 1425596Read ↗

Activity of promoter mutants of the yeast ribosomal RNA gene with and without the enhancer.Semantic proximity Read ↗

The yeast RNA polymerase I promoter: ribosomal DNA sequences involved in transcription initiation and complex formation in vitro.Semantic proximity Read ↗

Different roles for abf1p and a T-rich promoter element in nucleosome organization of the yeast RPS28A gene.Semantic proximity Read ↗

In vitro definition of the yeast RNA polymerase I promoter.Semantic proximity Read ↗

Ribosomal gene promoter domains can function as artificial enhancers of RNA polymerase I transcription, supporting a promoter origin for natural enhancers in Xenopus.Semantic proximity Read ↗

Identification of DNA cis elements essential for expansion of ribosomal DNA repeats in Saccharomyces cerevisiae.Semantic proximity Read ↗

Analysis of the rat ribosomal DNA promoter: characterization of linker-scanning mutants and of the binding of UBF.Semantic proximity Read ↗

REB1, a yeast DNA-binding protein with many targets, is essential for growth and bears some resemblance to the oncogene myb.Semantic proximity Read ↗

Interaction of transcriptional regulators with specific nucleosomes across the Saccharomyces genome.Semantic proximity Read ↗

Multiprotein transcription factor UAF interacts with the upstream element of the yeast RNA polymerase I promoter and forms a stable preinitiation complex.Semantic proximity Read ↗

Hmo1 directs pre-initiation complex assembly to an appropriate site on its target gene promoters by masking a nucleosome-free region.Semantic proximity Read ↗

High resolution studies of the Xenopus laevis ribosomal gene promoter in vivo and in vitro.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.