Article
Assimilation of nicotinamide mononucleotide requires periplasmic AphA phosphatase in Salmonella enterica.
Journal of bacteriology - 1 Jul 2005
Grose Julianne H, Bergthorsson Ulfar, Xu Yaping, Sterneckert Jared, Khodaverdian Behzad, Roth John R
Abstract excerpt
Salmonella enterica can obtain pyridine from exogenous nicotinamide mononucleotide (NMN) by three routes. In route 1, nicotinamide is removed from NMN in the periplasm and enters the cell as the free base. In route 2, described here, phosphate is removed from NMN in the periplasm by acid phosphatase (AphA), and the produced nicotinamide ribonucleoside (NmR) enters the cell via the PnuC transporter. Internal NmR...
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