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Article

Isolation of NAD cycle mutants defective in nicotinamide mononucleotide deamidase in Salmonella typhimurium.

Journal of bacteriology - 1 Dec 1995

Cheng W, Roth J

Abstract excerpt

The NAD or pyridine nucleotide cycle is the sequence of reactions involved in the breakdown of NAD to nicotinamide mononucleotide (NMN) and regeneration of NAD. This cycle is fivefold more active during aerobic growth of Salmonella typhimurium and under this condition breaks down half of the NAD pool every 90 min. DNA ligase is known to convert NAD to NMN but is only a minor contributor to the NAD cycle during...

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Identifiers

PMID: 7592458
DOI: 10.1128/jb.177.23.6711-6717.1995
PMCID: PMC177533

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