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Article

Regulation of NAD metabolism in Salmonella typhimurium: molecular sequence analysis of the bifunctional nadR regulator and the nadA-pnuC operon.

Journal of bacteriology - 1 Aug 1990

Foster J W, Park Y K, Penfound T, Fenger T, Spector M P

Abstract excerpt

In Salmonella typhimurium, de novo synthesis of NAD is regulated through the transcriptional control of the nadA and nadB loci. Likewise, the pyridine nucleotide salvage pathway is controlled at pncB. The transcriptional expression of these three loci is coordinately regulated by the product of nadR. However, there is genetic evidence suggesting that NadR is bifunctional, serving in both regulatory and transport...

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Identifiers

PMID: 2198247
DOI: 10.1128/jb.172.8.4187-4196.1990
PMCID: PMC213241

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