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Article

L-selectin: mechanisms and physiological significance of ectodomain cleavage.

Journal of cellular and molecular medicine - 1 Jan 2000

Smalley D M, Ley K

Abstract excerpt

L-selectin is a cell adhesion molecule consisting of a large, highly glycosylated, extracellular domain, a single spanning transmembrane domain and a small cytoplasmic tail. It is expressed on most leukocytes and is involved in their rolling on inflamed vascular endothelium prior to firm adhesion and transmigration. It is also required for the constitutive trafficking of lymphocytes through secondary lymphoid...

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Identifiers

PMID: 15963248
DOI: 10.1111/j.1582-4934.2005.tb00354.x
PMCID: PMC6740228

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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