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Article

Tumor necrosis factor-alpha converting enzyme.

The international journal of biochemistry & cell biology - 1 Jan 2002

Black Roy A

Abstract excerpt

Tumor necrosis factor-alpha converting enzyme (TACE/ADAM17/CD156q) is a member of the 'A Disintegrin And Metalloprotease', or ADAM, family. It is a multi-domain, type I transmembrane protein that includes an extracellular zinc-dependent protease domain. TACE expression is largely constitutive, but the surface pool is downregulated following cell activation. Cleavage by TACE generates the soluble forms of tumor...

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Source

Identifiers

PMID: 11733179
DOI: 10.1016/s1357-2725(01)00097-8

Genes

ADAM17

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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