Article
Hepatitis C virus core protein and hepatitis activity are associated through transactivation of interleukin-8.
The Journal of infectious diseases - 15 Jul 2005
Hoshida Yujin, Kato Naoya, Yoshida Hideo, Wang Yue, Tanaka Masamichi, Goto Tadashi, Otsuka Motoyuki, Taniguchi Hiroyoshi, Moriyama Masaru, Imazeki Fumio, Yokosuka Osamu, Kawabe Takao, Shiratori Yasushi, Omata Masao
Abstract excerpt
BACKGROUND: We evaluated the association between variations in hepatitis C virus (HCV) core protein and hepatitis severity in patients with chronic HCV infection who achieved remission without viral eradication and had a biochemical response to interferon (IFN) therapy, to evaluate the effect of HCV core sequence in the absence of the influence of host factors. METHODS. Using serum from 10 patients with a...
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